The Department of Pharmaceutical Sciences

Graduate Research Forum

2010

 

September 30, 2010

8:30 am - 4:15 pm

Bent Hall 277A/B

 

                                                             

                                             Program

 

8:30 am

 

Welcome:  Dr. Louis Trombetta

Chair, Pharmaceutical Sciences

8:40 am–12:00 pm

 

Morning Session

12:00 -1:00 pm

 

Lunch

1:00 - 3:50 pm

 

Afternoon Session

    3:50  pm

 

Wrap up

 

 

 

 


                                                   Morning Session

 

8:40-8:48              Kelly Almond

                                The effects of copper pyrithione on zebrafish embryonic development.

Specialization:  Toxicology

Mentor:  Dr. Louis Trombetta

 

8:50-8:58              Swapnil Patwa

                                Design and synthesis of quinolinoxypyrimidines as TRPV1 antagonists.

Specialization:  Medicinal Chemistry

Mentor:  Dr. Vijaya Korlipara

 

9:00-9:08              Priyank Kumar

                                Identification of genes involved in autophagy.

Specialization:  Pharmacology

Mentor:  Dr. Kurt Degenhardt

 

9:10-9:18              Ramya Iyer

                                Evidence for a role of serotonin in side effects for metformin.

Specialization:  Toxicology

Mentor:  Dr. Raymond Ochs

 

9:20-9:28              Ritu Malla

                                Lovastatin stimulates hyperoxia-induced HMG-B1 release and rescues macrophage
dysfunction.

Specialization:  Pharmacology

Mentor:  Dr. Lin Mantell

 

9:30-9:38              Stephanie Liao

                                The protective role of zinc on cadmium-treated LLC-PK1 cells.

Specialization:  Toxicology

Mentor:  Dr. Sue Ford

 

9:40-9:48              Ankita V. Shah

                                Development of solid self-emulsifying lipid-based drug delivery systems using poloxamer 188,
 a non-ionic block copolymer as solidifying agent..

Specialization:  Pharmaceutics

Mentor:  Dr. Abu Serajuddin

 

9:50-9:58              Grishma Patel

                                Preparation and evaluation of targeted indocyanine green-loaded nanoparticles against ovarian cancer.

Specialization:  Industrial Pharmacy

Mentor:  Dr. Jun Shao

 

10:00-10:08         Sanket Gadhia

                                Heavy metals alter histone modification pathways in mouse embryo stem cells.

Specialization:  Pharmacology

Mentor:  Dr. Frank Barile

 

10:10-10:18         Mumtaz Akhtar

                                The effects of manganese-containing fungicide (Maneb) on rat hippocampal astrocytes.

Specialization:  Toxicology

Mentor:  Dr. Louis Trombetta

 

10:20-10:28         Swapna Munnangi

                                Pregnancy-associated plasma protein-A2: a novel biomarker for Down syndrome.

Specialization:  Pharmacology

Mentor:  Dr. Sandra E. Reznik

 

10:30-10:38         Aishwarya Sarma

                                OAT5 as a mediator of ochratoxin A toxicity in LLC-PK1 cells.

Specialization:  Toxicology

Mentor:  Dr. Sue Ford

 

10:40-10:48         Dhirender Singh

                                Brain targeting drug delivery by using magnetic nanoparticles.

Specialization:  Pharmaceutics

Mentor:  Dr. Emilio Squillante

 

10:50-10:58         Priyanka Madia

                                [35S]GTPγS binding and opioid tolerance in mouse spinal cord.

Specialization:  Pharmacology

Mentor:  Dr. Byron Yoburn

 

11:00-11:08         Shalini Roy

                                Comparison of toxicities of tellurium and selenium in rat hippocampal astrocytes.

Specialization:  Toxicology

Mentor:  Dr. Diane Hardej

 

11:10-11:18         Vivek S. Patel

                                HMGB1 in hyperoxia-compromised host ability to clear Pseudomonas aeruginosa pneumonia.

Specialization:  Toxicology

Mentor:  Dr. Lin Mantell

 

11:20-11:28         Krupanandan Haranahalli

                                Design and synthesis of N1-substituted-3-(3-carboxybenzyl)-4-oxo-6-propoxy-1,4-
dihydroquinolone-2-carboxylic acid derivatives as ETA agaonist.

Specialization:  Medicinal Chemistry

Mentor:  Dr. Ralph Stephani

 

11:30-11:38         Ravi Sitapara

                                HMGB1 impairs Pseudomonas aeruginosa clearance in cystic fibrosis lungs.

Specialization:  Pharmacology

Mentor:  Dr. Lin Mantell

 

11:40-11:48         Dipesh Navani

                                Precipitated opioid withdrawal by naltrexone and 6β-naltrexol:role of efficacy and
time-action profile.

Specialization:  Pharmacology

Mentor:  Dr. Byron Yobur

 

 

 

 

 

 


                                             LUNCH

 

 

 

 

 


                                                  Afternoon Session

 

1:00-1:08              Prathamesh R. Mahajan

                                Maneb toxicity on NrF-2 deficient mouse astrocytes.

Specialization:  Toxicology

Mentor:  Dr. Diane Hardej

 

1:10-1:18              Itti Bist

                                Design and synthesis of quinazoline derivatives as EGFR inhibitors.

Specialization:  Medicinal Chemistry

Mentor:  Dr. Vijaya Korlipara

 

1:20-1:28              Puneet Vij

                                Investigation of tellurium(IV) chloride and diphenyl ditelluride toxicity in human colon cells.

Specialization:  Toxicology

Mentor:  Dr. Diane Hardej

 

1:30-1:38              Ishwar Sadarangani

                                Resolution of diastereomers of N-1,N-3-disubstituted phthalidyl spirohydantoins and their
anticonvulsant activities.

Specialization:  Medicinal Chemistry

Mentor:  Dr. Ralph Stephani

 

1:40-1:48              Mabel N. Abraham

                                Analysis of gene expression patterns of manganese exposure in mice as potential biomarkers.

Specialization:  Toxicology

Mentor:  Dr. Marc Gillespie

 

1:50-1:58              Ying Ma

                                In vivo biodistribution of ICG-loaded targeted nanoparticles in nude mice with
MDAMB-231 tumor.

Specialization:  Pharmaceutics

Mentor:  Dr. Jun Shao

 

2:00-2:08              Christelle Adiabaiah

                                Cytotoxicity of several stilbene compounds on macrophages.

Specialization:  Toxicology

Mentor:  Dr. Blase Billack

 

2:10-2:18              Elizabeth Mathew

                                Comparison of taurine and insulin for their effects on oxidative stress by diabetes in
the heart and aorta of rats.

Specialization:  Pharmacology

Mentor:  Dr. Cesar Lau Cam

 

2:20-2:28              Kelly Garcia

                                Vanadium toxicity in LLC-PK1 cells.

Specialization:  Toxicology

Mentor:  Dr. Sue Ford

 

2:30-2:38              Vijetha Kode

                                Design of a self-degrading controlled drug delivery system for clonidine hydrochloride
by embedding "Candida Antarctica lipase B" in polycaprolactone nanoparticles.

Specialization:  Pharmaceutics

Mentor:  Dr. Mostafa Sadoqi

 

2:40-2:48              Lisa Hoffman

                                Ethylene bisdithiocarbamate pesticides Maneb and Mancozeb cause toxicity in
normal/transformed colon cells.

Specialization:  Toxicology

Mentor:  Dr. Diane Hardej

 

2:50-2:58              Rohan Nagavally

                                Regulation of P-glycoprotein in LLC-PK1 cells by glucose levels in culture media.

Specialization:  Toxicology

Mentor:  Dr. Sue Ford

 

3:00-3:08              Xingjian Liu

                                Effect of ETA-receptor antagonist on drug-induced pulmonary fibrosis.

Specialization:  Toxicology

Mentor:  Dr. Jerome Cantor

 

3:10-3:18              Trudi Denoon

                                Development of a rodent model for canine raisin nephrotoxicity.

Specialization:  Toxicology

Mentor:  Dr. Sue Ford

 

3:20-3:28              Satyakam Singh

                                Design and synthesis of novel PARP-1 inhibitors.

Specialization:  Medicinal Chemistry

Mentor:  Dr. Tanaji T. Talele

 

3:30-3:38              Jessica Placido

                                Analytical method validation for detection of novel co-metabolites of drugs of abuse and
ethanol in biological matrices.

Specialization:  Toxicology

Mentor:  Dr. Sandy Zito

 

3:40-3:48              Aaditya Bhatt

                                Design and synthesis of novel HIV-1 RT inhibitors.

Specialization:  Medicinal Chemistry

Mentor:  Dr. Tanaji T. Talele

 

3:50                        Wrap-up